Mendelian Crosses Made Easy - A step-by-step guide
1. Determine the traits to be used.
2. Know how the alleles are expressed. Which is dominant, which is recessive, etc.
3. Establish a letter symbol for each
trait. Use upper case and lower case letters for the dominant and recessive
alleles, respectively. You may have to use an alternative method for incomplete
dominance or codominance.
4. Determine the genotypes of the parents.
Keep alleles for each gene together and always write dominant alleles first.
5. Determine the gametes that are produced
by the parents. Remember that each parent makes their own gametes. Also, each
gamete has to get one allele of each gene (i,e, one letter from each trait).
6. Use random fertilization to combine the
gametes in all possible combinations. A Punnett
square can be used.
7. Determine the genotypes and phenotypes
of the offspring.
An alternate route:
1. Don't find 4 sex cells of each parent.
Instead, "FOIL" each gene pair from each parent. You will now be able
to write a probability as a fraction.
2. Use the rule of independent events (i.e.,
multiply the fractions for each gene together) to find the overall probability.
How to
Solve Genetics Problems - things to keep in mind
1. If an individual shows the recessive
trait, you know s/he is homozygous recessive.
2. If an individual expresses a dominant
trait that individual has AT LEAST one dominant allele.
3. If an intermediate phenotype or
blending of phenotypes is observed, expect incomplete dominance or codominance.
4. If a trait expresses itself
disproportionately in males or females, suspect sex-linkage.
5. Monohybrid heterozygous crosses result
in 3:1 phenotypic ratios.
6. Dihybrid
heterozygous crosses result in 9:3:3:1 phenotypic ratios.
7. Incomplete dominance and codominance result in 1:2:1 phenotypic ratios.