Genetic Mutations

Point Mutation - substitute one base for another

Original: A T A C A C
Mutant : T T A C A C

Frameshift Mutation - a base is either added or removed which causes a shift in the reading frame. Many genes affects

Original: A T A C A C A A G C C A
Mutant: A T T A C A C A A G C C A

Silent Mutation - a base is changed but the resulting amino acid is the same as in the non mutant DNA. No outward changes.

Original: A A A C A G
Mutant: A A G C A G

Nonsense Mutation - a codon is changed to a STOP codon

Original: A T A C C C A A A
Mutant: A T T C C C A A A

 

Transposon - Jumping Gene, a stretch of DNA that inserts itself into a different spot on a chromsome or another chromosome

*Mutations in DNA can cause a change in species --> Evolution
*HOX mutations can cause major changes in morphology